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CARD8 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00022900-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CARD8 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 43.23
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CARD8 antibody (H00022900-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00022900-T01
    CARD8 transfected lysate.
    Western Blot
    QC Testing of H00022900-T01
    Lane 1: CARD8 transfected lysate ( 44 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • CARD8
  • Gene Alias:
  • CARDINAL,DACAR,DKFZp779L0366,Dakar,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP,NDPP1,TUCAN
  • Gene Description:
  • caspase recruitment domain family, member 8
  • Gene Summary:
  • The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • CARD inhibitor of NF-kappaB-activating ligands,CARD8 isoform T47,CARD8 isoform T51,CARD8 isoform T60,apoptotic protein NDPP1,tumor up-regulated CARD-containing antagonist of caspase nine
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