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CARD8 (Human) Matched Antibody Pair

  • Catalog # : H00022900-AP22
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  • Specification
  • Product Description:
  • This antibody pair set comes with matched antibody pair to detect and quantify protein level of human CARD8.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve using recombinant protein ( H00022900-P01 ) as an analyte.

    QC Testing of H00022900-AP22
    Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
  • Supplied Product:
  • Antibody pair set content:
    1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-CARD8 (100 ug)
    2. Detection antibody: mouse purified polyclonal anti-CARD8 (20 ug)
    *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • ELISA Pair (Recombinant protein)
  • Gene Information
  • Gene Name:
  • CARD8
  • Gene Alias:
  • CARDINAL,DACAR,DKFZp779L0366,Dakar,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP,NDPP1,TUCAN
  • Gene Description:
  • caspase recruitment domain family, member 8
  • Gene Summary:
  • The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • CARD inhibitor of NF-kappaB-activating ligands,CARD8 isoform T47,CARD8 isoform T51,CARD8 isoform T60,apoptotic protein NDPP1,tumor up-regulated CARD-containing antagonist of caspase nine
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