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Last updated: 2017/6/18

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NLRP1 rabbit monoclonal antibody

  • Catalog # : H00022861-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NLRP1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NLRP1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NLRP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • NLRP1
  • Gene Name:
  • NLRP1
  • Gene Alias:
  • CARD7,CLR17.1,DEFCAP,DEFCAP-L/S,DKFZp586O1822,KIAA0926,NAC,NALP1,PP1044,SLEV1,VAMAS1
  • Gene Description:
  • NLR family, pyrin domain containing 1
  • Gene Summary:
  • This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
  • Other Designations:
  • NACHT, LRR and PYD containing protein 1,NACHT, leucine rich repeat and PYD (pyrin domain) containing 1,NACHT, leucine rich repeat and PYD containing 1,caspase recruitment domain protein 7,death effector filament-forming Ced-4-like apoptosis protein,nucleo
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