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Last updated: 2017/12/17
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LPHN1 purified MaxPab rabbit polyclonal antibody (D01P)MaxPab

  • Catalog # : H00022859-D01P
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human LPHN1 protein.
  • Immunogen:
  • LPHN1 (AAH19928.1, 1 a.a. ~ 201 a.a) full-length human protein.
  • Sequence:
  • MGLISHLERLMAEGKWGGTGVVEGMGMAEEGAGNGKAVWGMGRGKGERSPSLSSTFPQGRRSQVPGLGSGHPCSGRLDPKSQTPEAPGSGCVLSTCPGPLLSSLSGQPPQPPSLNSRGSIAPGHPSPAPALPFPQRWPLHLCSDLSPSLCPSFSHKCHEFSNIFGSQPAAAMNFVGLRGRGSRKELGGRGQVGGWRDPFCC
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of LPHN1 expression in transfected 293T cell line (H00022859-T04) by LPHN1 MaxPab polyclonal antibody.

    Lane 1: LPHN1 transfected lysate(20.80 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • LPHN1
  • Gene Alias:
  • CIRL1,CL1,LEC2
  • Gene Description:
  • latrophilin 1
  • Gene Summary:
  • This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms
  • Other Designations:
  • calcium-independent alpha-latrotoxin receptor 1,lectomedin-2
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