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SIAHBP1 (Human) Recombinant Protein (P02)

  • Catalog # : H00022827-P02
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  • Specification
  • Product Description:
  • Human SIAHBP1 full-length ORF ( AAH11979, 1 a.a. - 516 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 82.5
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00022827-P02
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Gene Name:
  • PUF60
  • Gene Alias:
  • Gene Description:
  • poly-U binding splicing factor 60KDa
  • Gene Summary:
  • The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene. [provided by RefSeq
  • Other Designations:
  • FBP interacting repressor,Ro ribonucleoprotein binding protein 1,Ro ribonucleoprotein-binding protein 1,fuse-binding protein-interacting repressor,poly-U binding splicing factor PUF60,pyrimidine tract binding splicing factor,siah binding protein 1
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