MRAS (Human) Recombinant Protein (P01)
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Specification
Product Description
Human MRAS full-length ORF ( NP_001078518.1, 1 a.a. - 208 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKSQKKKKKTKWRGDRATGTHKLQCVIL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.2
Interspecies Antigen Sequence
Mouse (96); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MRAS
Entrez GeneID
22808GeneBank Accession#
NM_001085049.1Protein Accession#
NP_001078518.1Gene Name
MRAS
Gene Alias
FLJ42964, M-RAs, R-RAS3, RRAS3
Gene Description
muscle RAS oncogene homolog
Omim ID
608435Gene Ontology
HyperlinkGene Summary
Members of the RAS superfamily of GTP-binding proteins, which includes MRAS, are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors.[supplied by OMIM
Other Designations
muscle and microspikes RAS
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Interactome
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Pathway
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Disease
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