IKZF3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
ZNFN1A3 transfected lysate.
Western Blot
Lane 1: ZNFN1A3 transfected lysate ( 56.1 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IKZF3 full-length
Host
Human
Theoretical MW (kDa)
56.1
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IKZF3 antibody (H00022806-B01) by Western Blots.
SDS-PAGE Gel
ZNFN1A3 transfected lysate.
Western Blot
Lane 1: ZNFN1A3 transfected lysate ( 56.1 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IKZF3
Entrez GeneID
22806GeneBank Accession#
NM_012481.3Protein Accession#
-Gene Name
IKZF3
Gene Alias
AIO, AIOLOS, ZNFN1A3
Gene Description
IKAROS family zinc finger 3 (Aiolos)
Omim ID
606221Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq
Other Designations
aiolos|zinc finger protein, subfamily 1A, 3 (Aiolos)
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Interactome
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Disease
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