ITGA11 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant ITGA11.
Immunogen
ITGA11 (NP_001004439, 793 a.a. ~ 893 a.a) partial recombinant protein with GST tag.
Sequence
LDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIECVNEERRLQKQVC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (87)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.22 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ITGA11
Entrez GeneID
22801GeneBank Accession#
NM_001004439Protein Accession#
NP_001004439Gene Name
ITGA11
Gene Alias
HsT18964
Gene Description
integrin, alpha 11
Omim ID
604789Gene Ontology
HyperlinkGene Summary
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq
Other Designations
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Pathway
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Disease
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Publication Reference
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TGF-beta enhances the integrin alpha2beta1-mediated attachment of mesenchymal stem cells to type I collagen.
Warstat K, Meckbach D, Weis-Klemm M, Hack A, Klein G, de Zwart P, Aicher WK.
Stem Cells and Development 2010 May; 19(5):645.
Application:Flow Cyt, Human, Mesenchymal stem cells.
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TGF-beta enhances the integrin alpha2beta1-mediated attachment of mesenchymal stem cells to type I collagen.
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