CASC3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CASC3 partial ORF ( NP_031385, 604 a.a. - 703 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
VSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CASC3
Entrez GeneID
22794GeneBank Accession#
NM_007359Protein Accession#
NP_031385Gene Name
CASC3
Gene Alias
BTZ, MLN51
Gene Description
cancer susceptibility candidate 3
Omim ID
606504Gene Ontology
HyperlinkGene Summary
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq
Other Designations
OTTHUMP00000164448|barentsz|metastatic lymph node 51
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