EXOSC8 monoclonal antibody (M01), clone 1G5
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant EXOSC8.
Immunogen
EXOSC8 (AAH20773, 1 a.a. ~ 276 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (93)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (56.1 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
EXOSC8 monoclonal antibody (M01), clone 1G5 Western Blot analysis of EXOSC8 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to EXOSC8 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EXOSC8 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — EXOSC8
Entrez GeneID
11340GeneBank Accession#
BC020773Protein Accession#
AAH20773Gene Name
EXOSC8
Gene Alias
CIP3, EAP2, OIP2, RP11-421P11.3, RRP43, Rrp43p, bA421P11.3, p9
Gene Description
exosome component 8
Omim ID
606019Gene Ontology
HyperlinkGene Summary
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq
Other Designations
CBP-interacting protein 3|OTTHUMP00000042274|Opa interacting protein 2|Opa-interacting protein 2
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Interactome
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Pathway
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