EXOSC8 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EXOSC8 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EXOSC8 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EXOSC8 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EXOSC8
Entrez GeneID
11340GeneBank Accession#
EXOSC8Gene Name
EXOSC8
Gene Alias
CIP3, EAP2, OIP2, RP11-421P11.3, RRP43, Rrp43p, bA421P11.3, p9
Gene Description
exosome component 8
Omim ID
606019Gene Ontology
HyperlinkGene Summary
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq
Other Designations
CBP-interacting protein 3|OTTHUMP00000042274|Opa interacting protein 2|Opa-interacting protein 2
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Interactome
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Pathway
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