MGAT4A monoclonal antibody (M02), clone 4H4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MGAT4A.
Immunogen
MGAT4A (NP_036346, 436 a.a. ~ 535 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PVNVESYLFHSGNQEHPGDILLNTTVEVLPFKSEGLEISKETKDKRLEDGYFRIGKFENGVAEGMVDPSLNPISAFRLSVIQNSAVWAILNEIHIKKATN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MGAT4A monoclonal antibody (M02), clone 4H4 Western Blot analysis of MGAT4A expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to MGAT4A on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.2 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MGAT4A is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — MGAT4A
Entrez GeneID
11320GeneBank Accession#
NM_012214Protein Accession#
NP_036346Gene Name
MGAT4A
Gene Alias
GNT-IV, GNT-IVA
Gene Description
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Omim ID
604623Gene Ontology
HyperlinkGene Summary
This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq
Other Designations
N-acetylglucosaminyltransferase IVa|OTTHUMP00000161122|UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV|UDP-N-acetylglucosamine:alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase|alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acet
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Interactome
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Pathway
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