PARK7 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human PARK7 full-length ORF ( NP_009193.2, 1 a.a. - 189 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.3
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PARK7
Entrez GeneID
11315GeneBank Accession#
NM_007262.3Protein Accession#
NP_009193.2Gene Name
PARK7
Gene Alias
DJ-1, DJ1, FLJ27376, FLJ34360, FLJ92274
Gene Description
Parkinson disease (autosomal recessive, early onset) 7
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000001348|OTTHUMP00000001349|OTTHUMP00000001350|OTTHUMP00000001351|Parkinson disease protein 7|oncogene DJ1|protein DJ-1
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Interactome
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Disease
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Publication Reference
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Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers.
Gabriela C Mauruto de Oliveira, Jefferson Henrique de Souza Carvalho, Laís Canniatti Brazaca, Nirton Cristi Silva Vieira, Bruno Campos Janegitz.
Biosensors & Bioelectronics 2020 Mar; 152:112016.
Application：Func, Synthetic urine samples.
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Improved detection of prostate cancer using a magneto-nanosensor assay for serum circulating autoantibodies.
Xu L, Lee JR, Hao S, Ling XB, Brooks JD, Wang SX, Gambhir SS.
PLoS One 2019 Aug; 14(8):e0221051.
Application：Func, Human, As a standard, Human serum.
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Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers.
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