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PARK7 rabbit monoclonal antibody

  • Catalog # : H00011315-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PARK7 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PARK7 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PARK7 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • PARK7
  • Gene Name:
  • PARK7
  • Gene Alias:
  • DJ-1,DJ1,FLJ27376,FLJ34360,FLJ92274
  • Gene Description:
  • Parkinson disease (autosomal recessive, early onset) 7
  • Gene Summary:
  • The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000001348,OTTHUMP00000001349,OTTHUMP00000001350,OTTHUMP00000001351,Parkinson disease protein 7,oncogene DJ1,protein DJ-1
  • Gene Pathway
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