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B4GALT7 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00011285-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human B4GALT7 protein.
  • Immunogen:
  • B4GALT7 (NP_009186.1, 1 a.a. ~ 327 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • B4GALT7 MaxPab polyclonal antibody. Western Blot analysis of B4GALT7 expression in HepG2.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of B4GALT7 expression in transfected 293T cell line (H00011285-T01) by B4GALT7 MaxPab polyclonal antibody.

    Lane 1: B4GALT7 transfected lysate(35.97 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • B4GALT7
  • Gene Alias:
  • B4GAL-T7,XGALT-1,XGALT1,XGPT1,beta4Gal-T7
  • Gene Description:
  • xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
  • Gene Summary:
  • This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) linkage found in proteoglycans. Manganese is required as a cofactor. This enzyme differs from the other six beta4GalTs because it lacks the conserved beta4GalT1-beta4GalT6 Cys residues and it is located in cis-Golgi instead of trans-Golgi. Two single-nucleotide mutations were identified from a patient with the progeroid type of Ehlers-Danlos syndrome. [provided by RefSeq
  • Other Designations:
  • beta-1,4-galactosyltransferase 7,galactosyltransferase 1 (xylosylprotein 4-beta-galactosyltransferase),xylosylprotein beta 1,4-galactosyltransferase 7
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