POU6F2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POU6F2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human POU6F2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POU6F2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POU6F2
Entrez GeneID
11281GeneBank Accession#
POU6F2Gene Name
POU6F2
Gene Alias
RPF-1, WT5, WTSL
Gene Description
POU class 6 homeobox 2
Gene Ontology
HyperlinkGene Summary
POU6F2 is a member of a gene family characterized by the presence of a bipartite DNA-binding domain, consisting of a POU-specific domain and a POU heterodomain, separated by a variable polylinker. POU domain family members are transcriptional regulators, many of which show highly restricted patterns of expression and are known to control cell type-specific differentiation pathways (see review by Phillips and Luisi, 2000 [PubMed 11183772]).[supplied by OMIM
Other Designations
POU domain, class 6, transcription factor 2|Wilms tumor suppressor locus|retina-derived POU-domain factor-1
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Interactome
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