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SCN11A Pre-design Chimera RNAi

  • Catalog # : H00011280-R01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens sodium channel, voltage-gated, type XI, alpha (SCN11A), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014139
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • SCN11A
  • Gene Alias:
  • NAV1.9,NaN,SCN12A,SNS-2
  • Gene Description:
  • sodium channel, voltage-gated, type XI, alpha subunit
  • Gene Summary:
  • Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM
  • Other Designations:
  • sodium channel, voltage-gated, type XI, alpha,sodium channel, voltage-gated, type XI, alpha polypeptide,sodium channel, voltage-gated, type XII, alpha polypeptide,voltage-gated sodium channel Nav1.9
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