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Last updated: 2016/10/23
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SCN11A monoclonal antibody (M04), clone 6E1

  • Catalog # : H00011280-M04
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant SCN11A.
  • Immunogen:
  • SCN11A (NP_054858, 1726 a.a. ~ 1791 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00011280-M04
    Western Blot detection against Immunogen (33 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged SCN11A is approximately 0.03ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
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  • Gene Information
  • Gene Name:
  • SCN11A
  • Gene Alias:
  • NAV1.9,NaN,SCN12A,SNS-2
  • Gene Description:
  • sodium channel, voltage-gated, type XI, alpha subunit
  • Gene Summary:
  • Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM
  • Other Designations:
  • sodium channel, voltage-gated, type XI, alpha,sodium channel, voltage-gated, type XI, alpha polypeptide,sodium channel, voltage-gated, type XII, alpha polypeptide,voltage-gated sodium channel Nav1.9
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