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TREX1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00011277-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TREX1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 40.7
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TREX1 antibody (H00011277-B02) by Western Blots.
    Western Blot
    QC Testing of H00011277-T02
    Lane 1: TREX1 transfected lysate ( 38.9 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00011277-T02
    TREX1 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • TREX1
  • Gene Alias:
  • AGS1,AGS5,CRV,DKFZp434J0310,DRN3,HERNS
  • Gene Description:
  • three prime repair exonuclease 1
  • Gene Summary:
  • This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 3' repair exonuclease 1,OTTHUMP00000164813,deoxyribonuclease III, dnaQ/mutD-like
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