TREX1 purified MaxPab rabbit polyclonal antibody (D03P)
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More Files
- More Functions
Western Blot (Tissue lysate)
TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in human pancreas.
Western Blot (Transfected lysate)
Western Blot analysis of TREX1 expression in transfected 293T cell line (H00011277-T04) by TREX1 MaxPab polyclonal antibody.
Lane 1: TREX1 transfected lysate(33.44 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TREX1 protein.
Immunogen
TREX1 (NP_009179.1, 1 a.a. ~ 304 a.a) full-length human protein.
Sequence
MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLRESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (74)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TREX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TREX1 expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of TREX1 expression in transfected 293T cell line (H00011277-T04) by TREX1 MaxPab polyclonal antibody.
Lane 1: TREX1 transfected lysate(33.44 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TREX1
Entrez GeneID
11277GeneBank Accession#
NM_007248.1Protein Accession#
NP_009179.1Gene Name
TREX1
Gene Alias
AGS1, AGS5, CRV, DKFZp434J0310, DRN3, HERNS
Gene Description
three prime repair exonuclease 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
3' repair exonuclease 1|OTTHUMP00000164813|deoxyribonuclease III, dnaQ/mutD-like
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Interactome
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Disease
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