SNF8 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SNF8 protein.
Immunogen
SNF8 (NP_009172.2, 1 a.a. ~ 258 a.a) full-length human protein.
Sequence
MHRRGVGAGAIAKKKLAEAKYKERGTVLAEDQLAQMSKQLDMFKTNLEEFASKHKQEIRKNPEFRVQFQDMCATIGVDPLASGKGFWSEMLGVGDFYYELGVQIIEVCLALKHRNGGLITLEELHQQVLKGRGKFAQDVSQDDLIRAIKKLKALGTGFGIIPVGGTYLIQSVPAELNMDHTVVLQLAEKNGYVTVSEIKASLKWETERARQVLEHLLKEGLAWLDLQAPGEAHYWLPALFTDLYSQEITAEEAREALP
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SNF8 expression in transfected 293T cell line (H00011267-T02) by SNF8 MaxPab polyclonal antibody.
Lane 1: SNF8 transfected lysate(28.90 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SNF8 on HeLa cell. [antibody concentration 30 ug/ml] -
Gene Info — SNF8
Entrez GeneID
11267GeneBank Accession#
NM_007241.2Protein Accession#
NP_009172.2Gene Name
SNF8
Gene Alias
Dot3, EAP30, VPS22
Gene Description
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
Omim ID
610904Gene Ontology
HyperlinkGene Summary
SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM
Other Designations
EAP30 subunit of ELL complex
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Interactome
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Pathway
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