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DUSP12 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00011266-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DUSP12 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 37.51
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DUSP12 antibody (H00011266-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00011266-T01
    DUSP12 transfected lysate.
    Western Blot
    QC Testing of H00011266-T01
    Lane 1: DUSP12 transfected lysate ( 37.51 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • DUSP12
  • Gene Alias:
  • DUSP1,YVH1
  • Gene Description:
  • dual specificity phosphatase 12
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032494,YVH1 protein-tyrosine phosphatase ortholog,serine/threonine specific protein phosphatase
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