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PADI2 Pre-design Chimera RNAi

  • Catalog # : H00011240-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens peptidyl arginine deiminase, type II (PADI2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_007365
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • PADI2
  • Gene Alias:
  • KIAA0994,PAD-H19,PAD2,PDI2
  • Gene Description:
  • peptidyl arginine deiminase, type II
  • Gene Summary:
  • This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002403,OTTHUMP00000044625,peptidlyarginine deiminase type II,protein arginine deiminase,protein-arginine deiminase type-2
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