POLG2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (73)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of POLG2 transfected lysate using rabbit polyclonal anti-POLG2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-POLG2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-POLG2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-POLG2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — POLG2
Entrez GeneID
11232Gene Name
POLG2
Gene Alias
HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB
Gene Description
polymerase (DNA directed), gamma 2, accessory subunit
Gene Ontology
HyperlinkGene Summary
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions
Other Designations
mitochondrial DNA polymerase, accessory subunit
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Interactome
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Pathway
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Disease
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