SEC63 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
SEC63 MaxPab polyclonal antibody. Western Blot analysis of SEC63 expression in human pancreas.
Western Blot (Cell lysate)
SEC63 MaxPab polyclonal antibody. Western Blot analysis of SEC63 expression in A-431.
Western Blot (Transfected lysate)
Western Blot analysis of SEC63 expression in transfected 293T cell line (H00011231-T01) by SEC63 MaxPab polyclonal antibody.
Lane 1: SEC63 transfected lysate(83.6 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SEC63 protein.
Immunogen
SEC63 (NP_009145.1, 1 a.a. ~ 760 a.a) full-length human protein.
Sequence
MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SEC63 MaxPab polyclonal antibody. Western Blot analysis of SEC63 expression in human pancreas.Western Blot (Cell lysate)
SEC63 MaxPab polyclonal antibody. Western Blot analysis of SEC63 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of SEC63 expression in transfected 293T cell line (H00011231-T01) by SEC63 MaxPab polyclonal antibody.
Lane 1: SEC63 transfected lysate(83.6 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SEC63
Entrez GeneID
11231GeneBank Accession#
NM_007214.3Protein Accession#
NP_009145.1Gene Name
SEC63
Gene Alias
ERdj2, PRO2507, SEC63L
Gene Description
SEC63 homolog (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq
Other Designations
OTTHUMP00000016937|SEC63-like|SEC63-like protein
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Interactome
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Disease
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