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Last updated: 2016/10/23
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DUSP10 polyclonal antibody (A01)

  • Catalog # : H00011221-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length recombinant DUSP10.
  • Immunogen:
  • DUSP10 (AAH20608, 1 a.a. ~ 140 a.a) full-length recombinant protein with GST tag.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00011221-A01
    Western Blot detection against Immunogen (41.51 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • DUSP10 polyclonal antibody (A01), Lot # 050928JC01 Western Blot analysis of DUSP10 expression in 293 ( Cat # L026V1 ).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • DUSP10
  • Gene Alias:
  • MKP-5,MKP5
  • Gene Description:
  • dual specificity phosphatase 10
  • Gene Summary:
  • Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035380,dual specificity phosphatase MKP-5,map kinase phosphatase 5,serine/threonine specific protein phosphatase
  • Gene Pathway
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