FZD10 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human FZD10 partial ORF ( NP_009128.1, 96 a.a. - 183 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKNDPNYLCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.42
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — FZD10
Entrez GeneID
11211GeneBank Accession#
NM_007197Protein Accession#
NP_009128.1Gene Name
FZD10
Gene Alias
CD350, FZ-10, FzE7, hFz10
Gene Description
frizzled homolog 10 (Drosophila)
Omim ID
606147Gene Ontology
HyperlinkGene Summary
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq
Other Designations
frizzled 10
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Interactome
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Pathway
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Disease
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