KLK8 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human KLK8 partial ORF ( NP_009127, 97 a.a. - 204 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.62
Interspecies Antigen Sequence
Mouse (72); Rat (72)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KLK8
Entrez GeneID
11202GeneBank Accession#
NM_007196Protein Accession#
NP_009127Gene Name
KLK8
Gene Alias
HNP, NP, NRPN, PRSS19, TADG14
Gene Description
kallikrein-related peptidase 8
Omim ID
605644Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq
Other Designations
KLK8 protein type 1|KLK8 protein type 2|kallikrein 8|kallikrein 8 (neuropsin/ovasin)|neuropsin type 1|neuropsin type 2|ovasin|protease, serine, 19|tumor-associated differentially expressed gene 14
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Interactome
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Disease
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