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KLK8 rabbit monoclonal antibody

  • Catalog # : H00011202-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human KLK8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human KLK8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human KLK8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • GeneBank Accession#:
  • KLK8
  • Gene Name:
  • KLK8
  • Gene Alias:
  • Gene Description:
  • kallikrein-related peptidase 8
  • Gene Summary:
  • Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq
  • Other Designations:
  • KLK8 protein type 1,KLK8 protein type 2,kallikrein 8,kallikrein 8 (neuropsin/ovasin),neuropsin type 1,neuropsin type 2,ovasin,protease, serine, 19,tumor-associated differentially expressed gene 14
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