PKP3 monoclonal antibody (M04), clone 6E5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PKP3.
Immunogen
PKP3 (NP_009114, 225 a.a. ~ 324 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGHLPDVHGFNSYGSHRTLQRLSSGFDDIDLPSA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PKP3 monoclonal antibody (M04), clone 6E5. Western Blot analysis of PKP3 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of PKP3 expression in transfected 293T cell line by PKP3 monoclonal antibody (M04), clone 6E5.
Lane 1: PKP3 transfected lysate (Predicted MW: 87.67 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PKP3 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — PKP3
Entrez GeneID
11187GeneBank Accession#
NM_007183Protein Accession#
NP_009114Gene Name
PKP3
Gene Alias
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Gene Description
plakophilin 3
Omim ID
605561Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. [provided by RefSeq
Other Designations
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Interactome
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Disease
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