NUDT3 monoclonal antibody (M01), clone 3C5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant NUDT3.
Immunogen
NUDT3 (AAH07727, 1 a.a. ~ 172 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MMKLKSNQTRTYDGDGYKKRAACLCFRSESEEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPVVATTYSVSAQSSMSGIR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (94)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (44.66 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NUDT3 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — NUDT3
Entrez GeneID
11165GeneBank Accession#
BC007727Protein Accession#
AAH07727Gene Name
NUDT3
Gene Alias
DIPP, DIPP1
Gene Description
nudix (nucleoside diphosphate linked moiety X)-type motif 3
Omim ID
609228Gene Ontology
HyperlinkGene Summary
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).[supplied by OMIM
Other Designations
OTTHUMP00000016227|diphosphoinositol polyphosphate phosphohydrolase|nudix-type motif 3
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