PTP4A3 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (42.39 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant PTP4A3.
Immunogen
PTP4A3 (AAH03105, 1 a.a. ~ 148 a.a) full-length recombinant protein with GST tag.
Sequence
MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (82)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.39 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PTP4A3
Entrez GeneID
11156GeneBank Accession#
BC003105Protein Accession#
AAH03105Gene Name
PTP4A3
Gene Alias
PRL-3, PRL-R, PRL3
Gene Description
protein tyrosine phosphatase type IVA, member 3
Omim ID
606449Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq
Other Designations
potentially prenylated protein tyrosine phosphatase
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Interactome
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Publication Reference
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8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy.
Fromont G, Godet J, Peyret A, Irani J, Celhay O, Rozet F, Cathelineau X, Cussenot O.
Human Pathology 2013 Aug; 44(8):1617.
Application：IHC, Human, Prostate cancer tissues.
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8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy.
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