CAPN11 monoclonal antibody (M04), clone 2G2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CAPN11.
Immunogen
CAPN11 (NP_008989, 557 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LLNRMAIKFKSFKTKGFGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVARY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (73)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CAPN11 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CAPN11
Entrez GeneID
11131GeneBank Accession#
NM_007058Protein Accession#
NP_008989Gene Name
CAPN11
Gene Alias
calpain11
Gene Description
calpain 11
Omim ID
604822Gene Ontology
HyperlinkGene Summary
Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq
Other Designations
OTTHUMP00000039887|calcium-activated neutral proteinase 11
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