FGFR1OP 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
FGFR1OP transfected lysate.
Western Blot
Lane 1: FGFR1OP transfected lysate ( 43.10 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FGFR1OP full-length
Host
Human
Theoretical MW (kDa)
43.1
Interspecies Antigen Sequence
Mouse (84); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FGFR1OP antibody (H00011116-D01P) by Western Blots.
SDS-PAGE Gel
FGFR1OP transfected lysate.
Western Blot
Lane 1: FGFR1OP transfected lysate ( 43.10 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FGFR1OP
Entrez GeneID
11116GeneBank Accession#
NM_007045Protein Accession#
NP_008976.1Gene Name
FGFR1OP
Gene Alias
FOP
Gene Description
FGFR1 oncogene partner
Omim ID
605392Gene Ontology
HyperlinkGene Summary
This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000017612|OTTHUMP00000017613|fibroblast growth factor receptor 1 oncogene partner
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Interactome
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Disease
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