WDR5 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human WDR5 full-length ORF ( NP_060058.1, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
63
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — WDR5
Entrez GeneID
11091GeneBank Accession#
NM_017588.2Protein Accession#
NP_060058.1Gene Name
WDR5
Gene Alias
BIG-3, SWD3
Gene Description
WD repeat domain 5
Omim ID
609012Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD-repeat protein 5
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Interactome
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Publication Reference
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Osteogenic genes related to the canonic WNT pathway are down-regulated in ameloblastoma.
Sathi GA, Tsujigiwa H, Ito S, Siar CH, Katase N, Tamamura R, Harada H, Nagatsuka H.
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 2012 Dec; 114(6):771.
Application:Added, Recombinant protein.
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Osteogenic genes related to the canonic WNT pathway are down-regulated in ameloblastoma.
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