WDR5 monoclonal antibody (M01), clone 2C2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant WDR5.
Immunogen
WDR5 (NP_060058, 16 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGK
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.29 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
WDR5 monoclonal antibody (M01), clone 2C2. Western Blot analysis of WDR5 expression in Hs 181.Tes.Western Blot (Cell lysate)
WDR5 monoclonal antibody (M01), clone 2C2. Western Blot analysis of WDR5 expression in A-549 ( Cat # L025V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged WDR5 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to WDR5 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — WDR5
Entrez GeneID
11091GeneBank Accession#
NM_017588Protein Accession#
NP_060058Gene Name
WDR5
Gene Alias
BIG-3, SWD3
Gene Description
WD repeat domain 5
Omim ID
609012Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD-repeat protein 5
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Interactome
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