TOPBP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TOPBP1 partial ORF ( NP_008958, 1327 a.a. - 1435 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Mouse (66)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TOPBP1
Entrez GeneID
11073GeneBank Accession#
NM_007027Protein Accession#
NP_008958Gene Name
TOPBP1
Gene Alias
TOP2BP1
Gene Description
topoisomerase (DNA) II binding protein 1
Omim ID
607760Gene Ontology
HyperlinkGene Summary
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq
Other Designations
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Interactome
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Disease
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