TOPBP1 monoclonal antibody (M04), clone 6D12
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More Files
- More Functions
Western Blot (Cell lysate)
TOPBP1 monoclonal antibody (M04), clone 6D12. Western Blot analysis of TOPBP1 expression in Jurkat.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TOPBP1 is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.73 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TOPBP1.
Immunogen
TOPBP1 (NP_008958, 1327 a.a. ~ 1435 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LLQSGGAKVLPGHSVPLFKEATHLFSDLNKLKPDDSGVNIAEAAAQNVYCLRTEYIADYLMQESPPHVENYCLPEAISFIQNNKELGTGLSQKRKAPTEKNKIKRPRVH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TOPBP1 monoclonal antibody (M04), clone 6D12. Western Blot analysis of TOPBP1 expression in Jurkat.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TOPBP1 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — TOPBP1
Entrez GeneID
11073GeneBank Accession#
NM_007027Protein Accession#
NP_008958Gene Name
TOPBP1
Gene Alias
TOP2BP1
Gene Description
topoisomerase (DNA) II binding protein 1
Omim ID
607760Gene Ontology
HyperlinkGene Summary
This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq
Other Designations
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Interactome
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Disease
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