LILRA3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
LILRA3 transfected lysate.
Western Blot
Lane 1: LILRA3 transfected lysate ( 48.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-LILRA3 full-length
Host
Human
Theoretical MW (kDa)
48.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-LILRA3 antibody (H00011026-B01) by Western Blots.
SDS-PAGE Gel
LILRA3 transfected lysate.
Western Blot
Lane 1: LILRA3 transfected lysate ( 48.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — LILRA3
Entrez GeneID
11026GeneBank Accession#
NM_006865.2Protein Accession#
NP_006856.2Gene Name
LILRA3
Gene Alias
CD85E, HM31, HM43, ILT6, LIR-4, LIR4, e3
Gene Description
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Omim ID
604818Gene Ontology
HyperlinkGene Summary
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM
Other Designations
OTTHUMP00000067955|OTTHUMP00000067957|leucocyte immunoglobulin-like receptor|leukocyte immunoglobulin-like receptor 4|leukocyte immunoglobulin-like receptor A3
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Interactome
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Disease
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