KLK11 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human KLK11 full-length ORF ( NP_006844.1, 1 a.a. - 250 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
53.9
Interspecies Antigen Sequence
Mouse (81); Rat (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KLK11
Entrez GeneID
11012GeneBank Accession#
NM_006853.2Protein Accession#
NP_006844.1Gene Name
KLK11
Gene Alias
MGC33060, PRSS20, TLSP
Gene Description
kallikrein-related peptidase 11
Omim ID
604434Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed. [provided by RefSeq
Other Designations
hippostasin|kallikrein 11|protease, serine, 20 trypsin-like|protease, serine, trypsin-like
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Interactome
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Disease
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