IL24 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
IL24 transfected lysate.
Western Blot
Lane 1: IL24 transfected lysate ( 23.80 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IL24 full-length
Host
Human
Theoretical MW (kDa)
23.8
Interspecies Antigen Sequence
Mouse (66); Rat (63)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IL24 antibody (H00011009-D01P) by Western Blots.
SDS-PAGE Gel
IL24 transfected lysate.
Western Blot
Lane 1: IL24 transfected lysate ( 23.80 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IL24
Entrez GeneID
11009GeneBank Accession#
NM_006850Protein Accession#
NP_006841.1Gene Name
IL24
Gene Alias
C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7
Gene Description
interleukin 24
Omim ID
604136Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
IL-24 splice variant delE3|IL-24 splice variant delE5|OTTHUMP00000034620|melanoma differentiation association protein 7|suppression of tumorigenicity 16 (melanoma differentiation)
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Interactome
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Pathway
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Disease
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