LILRB4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LILRB4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LILRB4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LILRB4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LILRB4
Entrez GeneID
11006GeneBank Accession#
LILRB4Gene Name
LILRB4
Gene Alias
CD85K, HM18, ILT3, LILRB5, LIR-5, LIR5
Gene Description
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
Omim ID
604821Gene Ontology
HyperlinkGene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000068605|OTTHUMP00000068606|immunoglobulin-like transcript 3|leukocyte immunoglobulin-like receptor 5|leukocyte immunoglobulin-like receptor subfamily B member 4 soluble isoform|leukocyte immunoglobulin-like receptor, subfamily B, member 4|monoc
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Interactome
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+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
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