SLC27A2 monoclonal antibody (M01), clone 1F1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC27A2.
Immunogen
SLC27A2 (NP_003636, 25 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YFFQDIGYFLKVAAVGRRVRSYGQRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (76)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC27A2 is 1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to SLC27A2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — SLC27A2
Entrez GeneID
11001GeneBank Accession#
NM_003645Protein Accession#
NP_003636Gene Name
SLC27A2
Gene Alias
ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1
Gene Description
solute carrier family 27 (fatty acid transporter), member 2
Omim ID
603247Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
very long-chain fatty-acid-coenzyme A ligase 1|very-long-chain acyl-CoA synthetase
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