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Last updated: 2016/10/23
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SF3B2 monoclonal antibody (M10), clone 2A2

  • Catalog # : H00010992-M10
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant SF3B2.
  • Immunogen:
  • SF3B2 (AAH07610, 1 a.a. ~ 636 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00010992-M10
    Western Blot detection against Immunogen (95.48 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • SF3B2 monoclonal antibody (M10), clone 2A2. Western Blot analysis of SF3B2 expression in Hela S3 NE ( Cat # L013V3 ).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • SF3B2
  • Gene Alias:
  • SAP145,SF3B145,SF3b1,SF3b150
  • Gene Description:
  • splicing factor 3b, subunit 2, 145kDa
  • Gene Summary:
  • This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq
  • Other Designations:
  • pre-mRNA splicing factor SF3b 145 kDa subunit,spliceosome associated protein 145,splicing factor 3B subunit 2
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