LILRB5 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human LILRB5 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — LILRB5
Entrez GeneID
10990GeneBank Accession#
NM_006840.2Protein Accession#
NP_006831.1Gene Name
LILRB5
Gene Alias
CD85C, LIR-8, LIR8
Gene Description
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
Omim ID
604814Gene Ontology
HyperlinkGene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
leukocyte immunoglobulin-like receptor 8|leukocyte immunoglobulin-like receptor, subfamily B, member 5
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