IMMT monoclonal antibody (M01), clone 1A8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IMMT.
Immunogen
IMMT (NP_006830, 481 a.a. ~ 580 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TQLRRQAAAHTDHLRDVLRVQEQELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAHQLWLSVEALKYSM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (80)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — IMMT
Entrez GeneID
10989GeneBank Accession#
NM_006839Protein Accession#
NP_006830Gene Name
IMMT
Gene Alias
DKFZp779P1653, HMP, MGC111146, P87, P87/89, P89, PIG4, PIG52
Gene Description
inner membrane protein, mitochondrial (mitofilin)
Omim ID
600378Gene Ontology
HyperlinkGene Summary
O
Other Designations
cell proliferation-inducing protein 52|inner membrane protein, mitochondrial|mitofilin|motor protein|proliferation-inducing gene 4
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Interactome
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Publication Reference
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SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, Des Rosiers C, Forest A, Lin ZY, Gingras AC, Mitchell G, McBride HM, Shoubridge EA.
EMBO Molecular Medicine 2016 Sep; 8(9):1019.
Application:IP, Human, Fibroblasts.
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SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
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