METAP2 293T Cell Transient Overexpression Lysate(Denatured)

Catalog # H00010988-T02

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Size:100 uL
Price: USD $ 247.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
SDS-PAGE Gel
QC Test

SDS-PAGE Gel

METAP2 transfected lysate.

Western Blot
QC Test

Western Blot

Lane 1: METAP2 transfected lysate ( 52.90 KDa)
Lane 2: Non-transfected lysate.

  • Specification

    Transfected Cell Line

    293T

    Plasmid

    pCMV-METAP2 full-length

    Host

    Human

    Theoretical MW (kDa)

    52.9

    Interspecies Antigen Sequence

    Mouse (94); Rat (93)

    Quality Control Testing

    Transient overexpression cell lysate was tested with Anti-METAP2 antibody (H00010988-B01P) by Western Blots.

    SDS-PAGE Gel

    METAP2 transfected lysate.

    Western Blot

    Lane 1: METAP2 transfected lysate ( 52.90 KDa)
    Lane 2: Non-transfected lysate.

    Storage Buffer

    1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

  • Gene Info — METAP2

    Entrez GeneID

    10988

    GeneBank Accession#

    NM_006838

    Protein Accession#

    NP_006829.1

    Gene Name

    METAP2

    Gene Alias

    MAP2, MNPEP, p67, p67eIF2

    Gene Description

    methionyl aminopeptidase 2

    Omim ID

    601870

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq

    Other Designations

    eIF-2-associated p67 homolog|initiation factor 2-associated 67 kDa glycoprotein|peptidase M 2

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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