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Last updated: 2017/9/17

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METAP2 Pre-design Chimera RNAi

  • Catalog # : H00010988-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens methionyl aminopeptidase 2 (METAP2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006838
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • METAP2
  • Gene Alias:
  • MAP2,MNPEP,p67,p67eIF2
  • Gene Description:
  • methionyl aminopeptidase 2
  • Gene Summary:
  • This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq
  • Other Designations:
  • eIF-2-associated p67 homolog,initiation factor 2-associated 67 kDa glycoprotein,peptidase M 2
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