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Last updated: 2016/10/23

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METAP2 mouse monoclonal antibody (hybridoma)

  • Catalog # : H00010988-M
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant METAP2.
  • Immunogen:
  • METAP2 (NP_006829.1, 1 a.a. ~ 478 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactivity and specificity confirmed by ELISA and Western Blot.
  • Note:
  • Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
  • Deliverables:
  • Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • METAP2
  • Gene Alias:
  • MAP2,MNPEP,p67,p67eIF2
  • Gene Description:
  • methionyl aminopeptidase 2
  • Gene Summary:
  • This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq
  • Other Designations:
  • eIF-2-associated p67 homolog,initiation factor 2-associated 67 kDa glycoprotein,peptidase M 2
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