Immunoprecipitation of MAPRE2 transfected lysate using anti-MAPRE2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with MAPRE2 MaxPab mouse polyclonal antibody (B02) (H00010982-B02).
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. Alternative splicing results in multiple transcript variants. [provided by RefSeq
APC-binding protein EB1,T-cell activation protein, EB1 family